Pepti-Acne Acne affects 50 million Americans annually. Estimates state that at least 85% of individuals experience some form of breakout between the ages of 12-24. There are five primary contributors to the acneic condition. Last Update: May 11, 2019 October 27, 2018 2466Technical DocumentsRelated Knowledge Base Posts -Rejuvenator or RetinolPepti-HyaluronicVitamin A: Retinoids and Carotenoids